MAFLD and risk of CKD

Background/aimsWhereas nonalcoholic fatty liver disease (NAFLD) is a multisystem disease, the association between metabolic dysfunction-associated (MAFLD) and extra-hepatic diseases not known. The aim of this cross-sectional study was to compare prevalence chronic kidney (CKD) in patients with either MAFLD or NAFLD, then examine presence severity CKD abnormal albuminuria.MethodsA total 12,571 individuals complete biochemical ultrasonography data from Third National Health Nutrition Examination Survey (1988–1994) were included analysis. Multivariable logistic regression analyses performed test independence associations as key exposures (defined stage ≥1 ≥3) albuminuria (urinary albumin-to-creatinine ratio ≥ 3 mg/mmol) outcomes.ResultsThe NAFLD 30.2% (n = 3794) 36.2% 4552), respectively. had lower eGFR (74.96 ± 18.21 vs. 76.46 18.24 ml/min/1.73 m2, P < 0.001) greater (29.60% 26.56%, 0.05) than individuals. Similarly, there higher non-metabolic (P 0.05). Notably, after adjustment for sex, age, ethnicity, alcohol intake diabetes, (i.e. fibrosis score 0.676) associated 1.34-fold risk prevalent 0.05).ConclusionsMAFLD identifies better NAFLD. increased are strongly independently albuminuria.